Women n=16
+17.8%avg. hair count change ยท p<.001
+21.0%frontal hair count (p<.001)
+31.74%average TVR change
Clinical study ยท Skin and Cancer Foundation Inc. ยท 2026
17.4% more hair on average in 6 months.
We tested the actual products, not just their ingredients. We gave the HairSmart Protocol to 30 men and women with pattern hair loss, and dermatologists measured every scalp for 6 months.
Men & women
100% drug-free ยท botanical
Hair count gain statistically significant
30 of 30
Increased hair count
100% of participants
+23.98%
Average TVR change
Group-average change not statistically significant (p=.626)
52%
Better quality of life
DLQI ยท p<.001
0
Side effects reported
Across all 30 participants
Individual results vary.
Results at 6 months
The numbers, no spin.
Men n=14
+16.9%avg. hair count change ยท p<.001
+16.1%frontal hair count (p<.001)
+15.12%average TVR change
Change from baseline at 6 months
Hair count and TVR rose for all participants, women and men.
Hair count
Change in hairs per cmยฒ, p<.001 for all three
+17.38%
+17.80%
+16.90%
Totaln=30
Womenn=16
Menn=14
TVR
Terminal-to-vellus hair ratio, average change
+23.98%
+31.74%
+15.12%
Totaln=30
Womenn=16
Menn=14
Source: statistical analysis by the Department of Dermatology, Skin and Cancer Foundation Inc. Hair count by TrichoScan, Wilcoxon signed-rank test. Hair count and TVR percentages are the average of each participant's individual percentage change. Individual results vary.
Disclosure: study commissioned by HairSmart; statistical analysis by the Department of Dermatology, Skin and Cancer Foundation Inc. (Beltejar & Mulato, 2026). Open-label study with no placebo group. Photos used with written consent.
TrichoScan before & after
Real participants. Real results.
Before ยท MNF2
6 months ยท MNF2
Case Study 01
Patient MNF2 ยท Woman, 50
- Patient ID
- Age / Gender
- Hair loss type
- Severity
- Protocol
- Duration
Patient IDs match the full study report. Individual results vary.
Quality of life
Hair loss bothered them half as much
After 6 months, participants said hair loss affected their confidence, social life and daily routine far less.
52%
improvement in quality of lifeAll participants ยท p<.001
62%
improvement ยท women
p<.00134%
improvement ยท men
p=.098 ยท not statistically significant44%
of women said hair loss no longer affected their daily life, up from 0%
Measured with the Dermatology Life Quality Index (DLQI), a standard 10-question survey on how a scalp or skin condition affects daily life. Average scores fell from 9.2 to 4.4 (lower is better).
The protocol studied
What participants took daily
The exact products you can buy. Participants took the same formulas we sell, not special research versions. Our supplements contain no fillers, flow agents or gelatin, dairy, wheat and soy.
Women's protocol
Protect DHT Blocker
Saw palmetto, stinging nettle, pygeum bark, pumpkin seed and green tea extracts.
H5 Growth+ Hair Vitamin
8 Ayurvedic botanicals (Bhringraj, Brahmi, Amla, Ashwagandha, Turmeric, Fenugreek, Neem, Nettle root), 5,000 mcg biotin, amino acids, vitamins and minerals.
Growth Accelerator Serum
Topical serum with Anantmool, Amla, Neem, onion bulb extract, hydrolyzed keratin and amino acids.
Men's protocol
Protect DHT Blocker
Saw palmetto, stinging nettle, pygeum bark, pumpkin seed and green tea extracts.
H5 Growth+ Hair Vitamin
8 Ayurvedic botanicals (Bhringraj, Brahmi, Amla, Ashwagandha, Turmeric, Fenugreek, Neem, Nettle root), 5,000 mcg biotin, amino acids, vitamins and minerals.
How the study worked
We counted hairs, not opinions
- Design
- Open-label, single-group, before-and-after study
- Duration
- 6 months, daily use; visits at baseline, 3 and 6 months
- Condition studied
- Androgenetic alopecia (male and female pattern hair loss)
- Participants
- 30 adults: 16 women, 14 men, ages 29โ74
- Hair loss grade
- Norwood IIโVI (men), Ludwig IโIII (women)
- Sites
- Minnesota, USA (7) and the Philippines (23)
- Measures
- Hair count per cmยฒ and terminal-to-vellus ratio by TrichoScan/ Hair metrics, in the same marked scalp zones at every visit, with no needles or biopsies; quality of life by DLQI
- Statistics
- Wilcoxon signed-rank test, two-sided, ฮฑ=0.05
The doctors behind the study
Dr. Ronald Shapiro, MD
Investigator, Minnesota site
Medical Director, Hair Transplant Specialists. ABHRS Diplomate.ProfileLinkedIn
Dr. Mariel Arambulo, MD, FPDS
Investigator, Philippines site
Dermatologist, Asian Hair Restoration Center.LinkedIn
Dr. Bea Mergie T. Beltejar, MD
Statistical analysis & report, Dept. of Dermatology, Skin and Cancer Foundation Inc.
Dermatology Resident, Skin and Cancer Foundation Inc.
Dr. Penelope V. Mulato, MD
Statistical analysis & report, Dept. of Dermatology, Skin and Cancer Foundation Inc.
Dermatology Resident, Skin and Cancer Foundation Inc.Safety record
0 side effects reported in 6 months
Across all 30 participants, men and women. No scalp irritation, allergic reactions or medication interactions.
Physician-monitored
Every participant was examined by a doctor at baseline, 3 months and 6 months.
Drug-free
A botanically derived regimen, with no prescription drugs.
Check with your doctor first
Especially if you are pregnant or nursing, take medication, or manage a medical condition.
What's next: the study is being prepared for publication, and a larger controlled study is planned.
Questions about the study
No. Most brands rely on published research on individual ingredients. We tested our actual products, on real people with pattern hair loss, measured by dermatologists.
It was an open-label, single-group, before-and-after study. 30 adults (16 women, 14 men, ages 29โ74) took the protocol daily for 6 months, with visits at baseline, 3 and 6 months. Hair count and terminal-to-vellus ratio were measured by TrichoScan in the same marked scalp zones at every visit, with no needles or biopsies.
It means a change is unlikely to be down to chance alone. We used a Wilcoxon signed-rank test (two-sided, ฮฑ=0.05). The hair count gains were significant at p<.001 for all participants, for women and for men.
TVR is the terminal-to-vellus hair ratio: how many thick, mature (terminal) hairs there are compared with fine, short (vellus) ones. A higher ratio means more mature hair. We report the average of each participant's percentage change from baseline to 6 months.
The study tested the full HairSmart protocol: the Protect DHT Blocker and H5 Growth+ Vitamin taken together daily, plus the Growth Accelerator Serum. The results reflect that combination. The DHT Blocker targets the hormonal root cause, the H5 Growth+ Vitamin provides the nutritional support follicles need to function, and the serum delivers actives directly to the scalp.
We also offer products individually for customers who want to build their routine gradually. If youโre not sure where to start, the hair quiz matches you to a protocol based on your hair loss type and goals.
The study measured results at 3 and 6 months, and the data show that improvement continued between those two time points. Hair growth is a slow biological process. The hair cycle takes months. Most participants in the study started noticing changes between months 2 and 4, with the clearest visible results appearing closer to months 5 and 6.
With any supplement routine, consistency matters. If you stop after 6 months, the underlying cause of your hair loss (DHT, nutrient deficiency, inflammation) doesnโt stop. Most people who see results continue using the protocol to maintain them.
No. Zero side effects were reported across all 30 participants over 6 months.
No scalp irritation. No allergic reactions. No medication interactions. Every participant was examined by a doctor at baseline, 3 months, and 6 months. The clean safety record was physician-monitored throughout.
Clinically studied. Ready to use at home.
Beltejar & Mulato (2026). Includes methods, results by sex, scalp region and grade, participant-level data, before/after images and the full safety log. Providers: request the statistical appendix.